Dpends on the game and location. If you play magfed in a cqb event a pistol stands up well. .43 work well. Their smaller than .68s and you get more shots off a sparklet. The chron at 250 which drops off after 6 mags of 10 to around 150.
.43 pistols are a handy size allowing you to vest mount.
Serpa holsters are good for that. But if chest mounted can get in the way if moving your stock of your primary from shoulder to shoulder.
You are however now needing to carry two types of rounds now. Plus most .43 pistols have horrible reliability and range. They really are more of a last ditch close range self defence item. Or indoor CQB where wind will not be a factor.
It was reasonably popular among pistol players a couple of years ago.
.43 suffers slightly from being a non standard calibre. This can mean you are not able to use it, eg when events are site or trader paint only
Also clear paint events. I believe you can get .43 clear but this paint does vary and for the types of sites that go for clear paint events you will often not be allowed to bring your own as it does vary considerably with good and bad or terrible batches and degradability
With all that though you can always ask an organizer, and with some events some traders may be willing to bring .43 for you
You may also be able to ask about velocities, you might need to stick to the same velocity or may be allowed a different velocity due to the lower mass
Also people I've seen have been happy with their .43 pistols
As a .68 alternate the Tpx can take a FS capable breach and compatible magazines are available or standard ones can be modified
This is of course dependant on your opinion on the pistol size. It's about the same overall size but the grip is less fat